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The past years have seen a sturdy increase in the demand for cannabis and cannabis-derived products nationwide. Most of these products are enriched with cannabinoids, the naturally-occurring compounds in the cannabis plant.

The most popular of these cannabinoids is delta-9-tetrahydrocannabinol (THC). However, since the recent addition of hexahydrocannabinol (HHC), it has also shot up in popularity compared to the more traditional cannabinoids like CBD and THC.

Talking of HHC, it’s a relatively scarce substance that can only be produced naturally in small quantities. Therefore, most HHC on the market is semi-synthetic. However, its structure and effects are similar to THC. If you’re interested in this new cannabinol, continue reading to learn about what science says about HHC’s benefits and effects.

HHC – How It’s Extracted?


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Chemist Roger Adams made the discovery of HHC in the 1940s. By incorporating hydrogen into the THC molecule and changing its physical characteristics, he produced HHC.

A 1947 patent document contains the first description of the procedure, known as hydrogenation. Adams made hexahydrocannabinol from THC, but businesses that produce HHC products use hemp. The primary justification for this is legal.

Cannabidiol (CBD) from raw hemp is first extracted before making HHC. The CBD is isolated after distillation. This item has a powdery consistency and is typically sold independently as CBD isolate. The isolate is then transformed into a delta-8 concentrate with a minimum potency of 96%.

The D8 is then hydrogenated in HHC using two active catalysts, typically heavy metals. From there, the manufacturer has a unique approach. Many companies refer to their HHC production process as a “proprietary process” without providing many details.

Before putting a product on the market, businesses must perform several filtration steps to remove the metals.

What does Hartford Healthcare Say About the Safety of Taking HHC?

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As a novel cannabinoid, HHC has never been the subject of in-depth safety studies at the Hartford Healthcare organization, so any currently available data about its safety is circumstantial. As a result, we cannot confidently tell whether HHC is safe or unsafe.

In other words, no research has been done on the protracted consequences of HHC use in humans because it has only recently become available.

However, the adverse effects of HHC cannabinoids appear similar to those caused by consuming too much THC, based on anecdotal reports. These negative outcomes of HHC products include:

  • Dry mouth
  • Paranoia
  • Feelings of anxiousness
  • Fast heart rate
  • Changes in appetite
  • Insomnia
  • Red eyes
  • Dizziness

If you are concerned about the safety and toxicity of HHC products, ensure you get them from a place that tests them with a third-party lab. Making sure you receive the appropriate dose will lessen the likelihood of toxicity. These labs test the product’s quality and report on what’s inside.

What is the difference between THC and HHC, as per the scientists?

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HHC’s effect profile is comparable to THC’s psychoactive effects. It will make you feel euphoric, change how you perceive sight and sound, increase your appetite, and momentarily raise your heart rate. Some HHC users describe them as more relaxing than stimulating, placing them anywhere between delta 8 THC and delta 9 THC.

Since HHC shares several of THC’s therapeutic and health advantages thanks to its molecular structure, some studies have looked into its potential as a drug. Beta-HHC showed impressive painkilling effects in a rat study, but additional research is required to assess its range of health advantages fully.

How long do you need to wait to feel the Effects of HHC?

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The HHC’s effects appear to take longer than other hemp products. For comparison, you might not feel its effects for at least an hour.

But many claim that when they’re having fun at the compound, they can concentrate and multitask. Since each person is unique, the HHC experience might begin for you earlier than for the average user.

To ensure you reach the desired high, we advise slowly and gradually increasing your dosage. Something doesn’t necessarily have to be intoxicating for it to be enjoyable. Even though CBD is non-psychoactive, many users use it daily.

Does HHC cause you to feel high, then? Yes, in a nutshell, but not in the same way that THC in cannabis does. Although it is not as strong, the high is similar to THC. It seems to have a lower potency than delta-9 THC, somewhere between 70% and 80%.

Some people think it’s more powerful or comparable to delta-8. It’s been characterized by users as a euphoric high. The atmosphere is incredibly tranquil all around. Depending on your taste, it’s a wonderful way to begin or end your day.

Benefits of Consuming HHC Cannabinoid

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The advantages of hydrogenated cannabidiol (THC) products have likely already been experienced by those who keep up with the latest cannabis news. Despite this, HHC’s potential benefits are still unknown.


HHC Has Anti-Inflammatory Properties

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Due to its structural similarity to THC, there may be anti-inflammatory, anti-oxidative, and anti-emetic effects of HHC. That’s why HHC might be helpful for handling:

  • Neuropathy and other forms of chronic pain
  • loss of appetite
  • Intestinal distress and nausea
  • Muscle cramps caused by diseases like MS (MS)

HHC Can Be Effective In Reducing Stress

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According to the research, consuming HHC products is a great way to relax and unwind. However, not every effect has supporting evidence. Try it out if you’re having trouble calming down and getting your mind in the game.

If you use the product correctly and don’t exceed the suggested dosage, you shouldn’t have any problems. A negative outlook adds another layer of difficulty to the situation. Search for HHC candies if you have no luck getting rid of them.

Based on the research, those who took this substance reported feeling happier and more at ease. In addition, their levels of anxiety were lower than average. Therefore, HHC products aid in not only reducing stress but also coping with anxiety and depression.

HHC May Help Lower the Growth Of Cancer Cells

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In the meantime, a 2011 study investigated two HHC analogs, LYR-7 and LYR-8. It was discovered that the compounds might impede angiogenesis and tumor cell growth, a crucial step in the formation of tumors.

Studies published in 2010 show that the effects of HHC on rats are long-lasting. Aside from the scant research described in this section, there is no other evidence linking HHC to the purported benefits touted by manufacturers.

Of course, there are currently no human studies that offer any helpful information on this subject.

HHC Can Help People Fall Sleep

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A consistent sleep schedule is essential for combating stress. Typically, students and independent contractors disregard this crucial point and work until they cannot continue. No wonder they require rests and extended sleep to regain their breath.

Some excellent news: HHC products can help you get a serene slumber. Multiple studies have demonstrated that it induces relaxation and expedites sleep onset. Those who utilized HHC slept more soundly and extended than those who did not.

In a 1977 study, rats were tested for HHC. The researchers discovered that the cannabinoid shared some properties with narcotic analgesics, but there were significant differences. In a 2007 study, HU211 and HU243 were tested on mice.

It was discovered that HHC increased sleep duration by between 80 and 700 percent. The researchers also noted that the cannabinoid produced effects similar to delta-9-THC in mice, albeit with weaker pharmacological effects.

HHC Can Relax The Body

To help themselves wind down from a hectic day and get a restful night’s sleep, many people are considering incorporating cannabis use into their self-care routine.

Since HHC stimulates the same CB1 receptors in the brain that can modify one’s viewpoint and elicit a sense of euphoria, it is classified as a psychotropic substance.

In contrast to delta-9 THC, HHC is more like delta-8 THC in that it induces a state of calm rather than euphoria. The HHC high is a more easygoing and clear-headed alternative to the traditional marijuana high.

What Amount of HHC Should You Consume?

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Age, weight, and tolerance level are the three most important considerations when determining an appropriate dose of HHC, as with any psychoactive substance.

The overall effectiveness of HHC is close to that of delta-9 THC. As a starting point, however, a dose of 10–20 mg per serving, which is similar to the original or slightly reduced, is recommended.

Advantage number one for HHC is that it can pass a standard 12-panel drug test undetected. This makes it a good alternative for the THC compounds known as delta-8 and delta-10, which are detectable in large amounts in blood and urine drug tests.

For how long does HHC Stay In Your System?

HHC is likely to have a half-life in the body similar to other cannabinoids such as delta-8-THC, delta-9-THC, and delta-9-THC-O.

However, how long the effects last will determine how frequently and how much of these compounds are used. These compounds have an average half-life in the human body of 30 days. Nonetheless, there are examples of much longer times.

Will HHC Show Up On A Drug Test?

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Although it’s improbable, some people assert that HHC can trick drug tests. To begin, HHC is a close relative of THC. Since THC can be detected in a drug test, HHC will also be unable to hide from them.

Due to HHC’s similarities to THC, its metabolism in the body is very close to that of THC. Drug tests can pick up the metabolite formed when THC is broken down in the body.

However, tests at the US Drug Test Center are so sensitive that even trace amounts of any compound can be detected. Suppose you have to pass a drug test; you should stay away from HHC because it will likely show up.

Where is HHC Legal?

Even though HHC has the same intoxicating effects as THC, it is not considered illegal at the federal level. Delta 9 tetrahydrocannabinol concentrations below 0.3% are classified as hemp and hemp-derived cannabinoids. After the Agriculture Improvement Act of 2018‘s passing, these were decriminalized by the Drug Enforcement Administration (DEA).

Once HHC becomes ubiquitous, however, we anticipate further policy adjustments. The DEA will have more time to study the compound’s effects on human health. However, HHC is permitted by some states as a THC replacement. Any HHC product is legally safe for you to use at your discretion.

In general, it appears that the DEA’s statement permits the sale of HHC. Despite this, many states have chosen to ban the sale and use of HHC. These consist of the following:

  • Montana
  • Arkansas
  • Mississippi
  • Idaho
  • New York

In numerous other states, its legality is also questionable. In light of the law’s ambiguity, products like HHC gummies used in the remaining states come with some risk.


You don’t often see a new compound burst unto the cannabis scene and take the market by storm. So when this happens, there’s considerable business research interest surrounding it.

Despite its limited availability in the cannabis market, HHC has provided opportunities for scientific investigation into its long and short-term effects. As you can tell from the examples above, HHC has so far proved promising.